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ATG13 Rabbit pAb
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ES20862
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: ATG13 Rabbit pAb
反应性: Human; Mouse;Rat
别名: Autophagy-related protein 13
宿主: Rabbit
稀释比: IHC-p1:50-200 ,WB 1:1000-2000
免疫原: Synthesized peptide derived from human ATG13 AA range: 182-232
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 72kD
基因ID: 9776
蛋白序列: O75143
细胞定位: Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
研究背景: Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
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