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Acetyl Kine rabbit pAb
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ES20844
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Acetyl Kine rabbit pAb
反应性: Species independent
别名: YM3306
宿主: Rabbit
稀释比: WB: 1:1000-2000
免疫原: Recombinant Protein of Acetyl Kine
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
研究背景: Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) .Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis.Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport.The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases, and HDACs have become promising targets for anti-cancer drugs currently in development.
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