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Crystallin-αC rabbit pAb
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ES20776
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Crystallin-αC rabbit pAb
反应性: Human
别名: HSPB8; CRYAC; E2IG1; HSP22; PP1629; Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22
宿主: Rabbit
稀释比: WB: 1:500-1000
免疫原: Recombinant Protein of Crystallin-αC
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
实测条带: 22kD
基因ID: 26353
蛋白序列: Q9UJY1
细胞定位: Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.
研究背景: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],
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