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EAAT2 rabbit pAb
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ES20771
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: EAAT2 rabbit pAb
反应性: Human;Rat;Mouse
别名: Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)
宿主: Rabbit
稀释比: WB 1:1000-2000
免疫原: Synthetic Peptide of EAAT2 AA range: 370-420
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 62kD
基因ID: 6506
蛋白序列: P43004
细胞定位: Cell membrane ; Multi-pass membrane protein .
研究背景: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010],
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