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GAL4 Activation Domain rabbit pAb
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ES20744
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: GAL4 Activation Domain rabbit pAb
别名: YM3410
宿主: Rabbit
稀释比: WB: 1:10000-50000
免疫原: Recombinant Protein of GAL4 Activation Domain
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
研究背景: The GAL4 protein of Saccharomyces cerevisiae is one of the most thoroughly characterized transcriptional activators. Since the N-terminal 147 amino acid residues of GAL4 are sufficient to mediate specific and strong binding to DNA, but are incapable of efficient transcriptional activation , this protein fragment has frequently been used to confer specific DNA binding in experiments examining transcriptional activation functions of heterologous proteins. This approach is facilitated by the finding that higher eukaryotes lack endogenous proteins that enhance transcription from the consensus GAL4-binding site. Fusions between GAL4 (aa 1-147) and activating domains from a variety of transcriptional regulatory proteins can activate transcription in yeast, plant, insects and mammalian cells. A unique "two-hybrid" system has been developed using GAL4 fusions in yeast to identify specific protein-protein interactions.
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