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PEPC rabbit pAb
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ES20649
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PEPC rabbit pAb
反应性: Plants
别名: PGC; Gastricsin; Pepsinogen C
宿主: Rabbit
稀释比: WB: 1:2000-5000
免疫原: Synthetic Peptide of PEPC
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
实测条带: 105-109kD
细胞定位: extracellular space,extracellular exosome,
研究背景: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
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