CREB3L2; BBF2H7; Cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2; BBF2 human homolog on chromosome 7
宿主:
Rabbit
稀释比:
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原:
The antiserum was produced against synthesized peptide derived from human CREB3L2. AA range:269-318
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
58kD
基因ID:
64764
蛋白序列:
Q70SY1
细胞定位:
Endoplasmic reticulum membrane ; Single-pass type II membrane protein. ER membrane resident protein. Upon ER stress, translocated to the Golgi apparatus where it is cleaved. The cytosolic N-terminal fragment (processed cyclic AMP-responsive element-binding protein 3-like protein 1) is transported into the nucleus. .; [Processed cyclic AMP-responsive element-binding protein 3-like protein 2]: Nucleus. Upon ER stress, translocated into the nucleus. .
研究背景:
This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],