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Connexin-26 rabbit pAb
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ES2029
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Connexin-26 rabbit pAb
反应性: Human;Mouse;Rat
别名: GJB2; Gap junction beta-2 protein; Connexin-26; Cx26
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Connexin-26. AA range:45-94
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 26kD
基因ID: 2706
蛋白序列: P29033
细胞定位: Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Colocalizes with GJB4 at gap junction plaques in the cochlea. .
研究背景: This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],
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