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COL4A6 rabbit pAb
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ES2024
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: COL4A6 rabbit pAb
反应性: Human;Rat;Mouse;
别名: COL4A6; Collagen alpha-6(IV) chain
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Collagen IV alpha6. AA range:1201-1250
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 160kD
基因ID: 1288
蛋白序列: Q14031
细胞定位: Secreted, extracellular space, extracellular matrix, basement membrane.
研究背景: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],
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