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14-3-3σ (Phospho Ser186) rabbit pAb
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ES20196
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: 14-3-3σ (Phospho Ser186) rabbit pAb
反应性: Human;Mouse
别名: 14-3-3 protein sigma (Epithelial cell marker protein 1;Stratifin)
宿主: Rabbit
稀释比: WB 1:1000-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human 14-3-3σ (Phospho Ser186)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 30kD
基因ID: 2810
蛋白序列: P31947
细胞定位: Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.
研究背景: function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,
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