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GABBR2 (Phospho Ser893) rabbit pAb
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ES20184
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: GABBR2 (Phospho Ser893) rabbit pAb
反应性: Human;Mouse;Rat
别名: Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2;GABA-B-R2;GABA-BR2;GABABR2;Gb2;G-protein coupled receptor 51;HG20)
宿主: Rabbit
稀释比: WB 1:1000-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human GABBR2 (Phospho Ser893)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 105kD
基因ID: 9568
蛋白序列: O75899
细胞定位: Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane. .
研究背景: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010],
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