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CtBP1/2 (Phospho Ser158/164) rabbit pAb
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ES20176
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CtBP1/2 (Phospho Ser158/164) rabbit pAb
反应性: Human;Mouse;Rat
别名: C-terminal-binding protein 1 (CtBP1;EC 1.1.1.-)
宿主: Rabbit
稀释比: WB 1:1000-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human CtBP1/2 (Phospho Ser158/164)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 48kD
基因ID: 1487
蛋白序列: Q13363/P56545
细胞定位: Cytoplasm . Nucleus .
研究背景: cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.,function:Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.,PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).,PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.,PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.,similarity:Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.,subunit:Interacts with the C-terminus of adenovirus E1A protein, ELK3 and CTIP via their consensus motif P-X-[DNS]-L-[STVA]. Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with FOXP2, HDAC4, HDAC5 and HDAC9. Interacts with GLIS2 but not GLIS1 or GLIS3 (By similarity). Interacts with FOXP1, HIPK2, PNN and NRIP1. Interacts with ZFHX1B and WIZ. Interacts with Epstein-Barr virus EBNA3 and EBNA6.,
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