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Claudin-19 rabbit pAb
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ES1986
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Claudin-19 rabbit pAb
反应性: Human;Rat
别名: CLDN19; Claudin-19
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 23kD
基因ID: 149461
蛋白序列: Q8N6F1
细胞定位: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
研究背景: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],
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