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CD137L rabbit pAb
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ES1894
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CD137L rabbit pAb
反应性: Human;Rat;Mouse;
别名: TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human TNFSF9. AA range:31-80
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 23kD
基因ID: 8744
蛋白序列: P41273
细胞定位: Membrane; Single-pass type II membrane protein.
研究背景: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided b
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