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53BP1 (phospho-Ser1778) rabbit pAb
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ES18530
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: 53BP1 (phospho-Ser1778) rabbit pAb
反应性: Human;Rat;Mouse;
别名: Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
宿主: Rabbit
稀释比: WB 1:1000-2000
免疫原: Synthesized phosho peptide around human 53BP1 (Ser1778)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 213kD
基因ID: 7158
蛋白序列: Q12888
细胞定位: Nucleus . Chromosome . Chromosome, centromere, kinetochore . Localizes to the nucleus in absence of DNA damage (PubMed:28241136). Following DNA damage, recruited to sites of DNA damage, such as double stand breaks (DSBs): recognizes and binds histone H2A monoubiquitinated at 'Lys-15' (H2AK15Ub) and histone H4 dimethylated at 'Lys-20' (H4K20me2), two histone marks that are present at DSBs sites (PubMed:23333306, PubMed:23760478, PubMed:24703952, PubMed:28241136, PubMed:17190600). Associated with kinetochores during mitosis (By similarity). .
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