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ADA11 rabbit pAb
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ES18463
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: ADA11 rabbit pAb
反应性: Human; Mouse
别名: Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human ADA11 AA range: 600-650
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 85kD
基因ID: 4185
蛋白序列: O75078
细胞定位: Membrane; Single-pass type I membrane protein.
研究背景: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],
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