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AL7A1 rabbit pAb
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ES18406
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: AL7A1 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human AL7A1 AA range: 229-279
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 59kD
基因ID: 501
蛋白序列: P49419
细胞定位: [Isoform 2]: Cytoplasm, cytosol . Nucleus .; [Isoform 1]: Mitochondrion .
研究背景: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011],
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