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ANO3 rabbit pAb
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ES18338
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: ANO3 rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human ANO3 AA range: 518-568
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 108kD
基因ID: 63982
蛋白序列: Q9BYT9
细胞定位: Cell membrane ; Multi-pass membrane protein . Shows an intracellular localization. .
研究背景: The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015],
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