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AP2B rabbit pAb
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ES18310
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: AP2B rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human AP2B AA range: 18-68
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 51kD
基因ID: 7021
蛋白序列: Q92481
细胞定位: Nucleus . In the brain, localizes to the arcuate hypothalamic nucleus, the ventromedial hypothalamic nucleus and the accumbens nucleus of the ventral striatum. .
研究背景: This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq, Jul 2008],
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