Synthesized peptide derived from human C8AP2 AA range: 1155-1205
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
218kD
基因ID:
9994
蛋白序列:
Q9UKL3
细胞定位:
Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.
研究背景:
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008],