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Caspase 10 (p23/17, Cleaved-Val220) Rabbit pAb
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ES17852
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Caspase 10 (p23/17, Cleaved-Val220) Rabbit pAb
反应性: Human; Mouse; Rat
别名: Caspase-10 (CASP-10;EC 3.4.22.63;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA(peptide)1:5000-20000
免疫原: Synthesized peptide derived from human Caspase 10 (p23/17, Cleaved-Val220)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 58+23kD
基因ID: 843
蛋白序列: Q92851
细胞定位: cytosol,CD95 death-inducing signaling complex,ripoptosome,
研究背景: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],
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