Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)
宿主:
Rabbit
稀释比:
WB 1:500-2000
免疫原:
Synthesized peptide derived from human CE112 AA range: 475-525
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
105kD
基因ID:
201134
蛋白序列:
Q8N8E3
细胞定位:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .
研究背景:
This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],