ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein
宿主:
Rabbit
稀释比:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
免疫原:
The antiserum was produced against synthesized peptide derived from human ATRIP. AA range:34-83
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
80kD
基因ID:
84126
蛋白序列:
Q8WXE1
细胞定位:
Nucleus . Redistributes to discrete nuclear foci upon DNA damage.
研究背景:
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],