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DHSO rabbit pAb
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ES16949
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: DHSO rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1：500-2000 IP 1:200
免疫原: Synthesized peptide derived from human DHSO
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 39kD
基因ID: 6652
蛋白序列: Q00796
细胞定位: Mitochondrion membrane ; Peripheral membrane protein . Cell projection, cilium, flagellum . Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface. .
研究背景: Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010],
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