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DUX4 rabbit pAb
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ES16875
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: DUX4 rabbit pAb
反应性: Human;Rat;Mouse;
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human DUX4 AA range: 235-285
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 47kD
蛋白序列: Q9UBX2
细胞定位: [Isoform 1]: Nucleus . Actively transported through the nuclear pore complex (NPC). .; [Isoform 2]: Nucleus .
研究背景: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
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