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ERLN2 rabbit pAb
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ES16681
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: ERLN2 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human ERLN2 AA range: 239-289
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 37kD
基因ID: 11160
蛋白序列: O94905
细胞定位: Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
研究背景: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012],
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