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FA11 rabbit pAb
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ES16586
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: FA11 rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human FA11 AA range: 491-540
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 69kD
基因ID: 2160
蛋白序列: P03951
细胞定位: Secreted.
研究背景: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008],
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