Synthesized peptide derived from human FAN AA range: 147-197
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
101kD
基因ID:
8439
蛋白序列:
Q92636
细胞定位:
cytoplasm,cytosol,endomembrane system,extrinsic component of membrane,
研究背景:
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],