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FBX22 rabbit pAb
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ES16505
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: FBX22 rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human FBX22 AA range: 182-232
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 44kD
基因ID: 26263
蛋白序列: Q8NEZ5
细胞定位: Cytoplasm, myofibril, sarcomere, Z line .
研究背景: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
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