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FBXW5 rabbit pAb
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ES16497
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: FBXW5 rabbit pAb
反应性: Human; Mouse;Rat
别名: F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human FBXW5 AA range: 319-369
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 60kD
基因ID: 54461
蛋白序列: Q969U6
细胞定位: Cytoplasm .
研究背景: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008],
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