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FHR5 rabbit pAb
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ES16472
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: FHR5 rabbit pAb
反应性: Human;Rat;Mouse;
别名: Complement factor H-related protein 5 (FHR-5)
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human FHR5 AA range: 353-403
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 60kD
基因ID: 81494
蛋白序列: Q9BXR6
细胞定位: Secreted.
研究背景: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],
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