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GEN rabbit pAb
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ES16215
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: GEN rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human GEN AA range: 61-111
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 100kD
基因ID: 348654
蛋白序列: Q17RS7
细胞定位: Nucleus .
研究背景: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],
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