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AChRα3 rabbit pAb
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ES1582
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: AChRα3 rabbit pAb
反应性: Human;Mouse;Rat
别名: CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human AChRalpha3. AA range:90-139
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 57kD
基因ID: 1136
蛋白序列: P32297
细胞定位: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein.
研究背景: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],
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