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IFIX rabbit pAb
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ES15528
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: IFIX rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human IFIX AA range: 338-388
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 54kD
基因ID: 149628
蛋白序列: Q6K0P9
细胞定位: [Isoform 1]: Nucleus, nucleoplasm.; [Isoform 3]: Nucleus, nucleoplasm.; [Isoform 5]: Nucleus. Nucleus speckle.
研究背景: The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],
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