产品中心

EpoR (phospho Tyr426) rabbit pAb
一键复制产品信息
ES1538
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
下载说明 ①

Overview

产品名称: EpoR (phospho Tyr426) rabbit pAb
反应性: Human;Mouse;Rat
别名: EPOR; Erythropoietin receptor; EPO-R
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: Synthesized phospho-peptide around the phosphorylation site of human EpoR (phospho Tyr426)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 55kD
基因ID: 2057
蛋白序列: P19235
细胞定位: Cell membrane; Single-pass type I membrane protein.; [Isoform EPOR-S]: Secreted . Secreted and located to the cell surface.
研究背景: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
关闭

在线咨询

Online consultation

  • 在线咨询
  • 技术支持

关注微信公众号

微信扫一扫立即咨询

微信电脑端咨询

微信扫一扫立即咨询

微信电脑端咨询
关闭