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MLK3 (phospho Ser674) rabbit pAb
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ES1535
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: MLK3 (phospho Ser674) rabbit pAb
反应性: Human;Mouse;Rat
别名: MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: Synthesized phospho-peptide around the phosphorylation site of human MLK3 (phospho Ser674)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 93kD
基因ID: 4296
蛋白序列: Q16584
细胞定位: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.
研究背景: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],
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