Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)
宿主:
Rabbit
稀释比:
WB 1:500-2000
免疫原:
Synthesized peptide derived from human LCTL AA range: 450-500
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
60kD
基因ID:
197021
蛋白序列:
Q6UWM7
细胞定位:
Endoplasmic reticulum membrane ; Single-pass membrane protein .
研究背景:
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],