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LOXL3 rabbit pAb
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ES15132
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: LOXL3 rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human LOXL3 AA range: 130-180
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 83kD
基因ID: 84695
蛋白序列: P58215
细胞定位: Secreted, extracellular space . Cytoplasm . Nucleus . It is unclear how LOXL3 is both intracellular (cytoplasmic and nuclear) and extracellular: it contains a clear signal sequence and is predicted to localize in the extracellular medium. However, the intracellular location is clearly reported and at least another protein of the family (LOXL2) also has intracellular and extracellular localization despite the presence of a signal sequence (PubMed:28065600). .; [Isoform 1]: Secreted, extracellular space .; [Isoform 2]: Cytoplasm . Secreted, extracellular space .
研究背景: This gene encodes a lysyl oxidase, which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate, spine deformity, and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome. [provided by RefSeq, Sep 2016],
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