Synthesized peptide derived from human LX15B AA range: 576-626
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
74kD
基因ID:
247
蛋白序列:
O15296
细胞定位:
[Isoform A]: Nucleus . Other isoforms are excluded from the nucleus. .; Cytoplasm, cytosol . Cell membrane . Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Cell junction, adherens junction . Cell junction, focal adhesion . Predominantly cytosolic; becomes enriched at membranes upon calcium binding. .
研究背景:
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],