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cGAS rabbit pAb
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ES15063
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: cGAS rabbit pAb
反应性: Human;Rat;Mouse;
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human M21D1 AA range: 35-85
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 57kD
基因ID: 115004
蛋白序列: Q8N884
细胞定位: Nucleus . Chromosome . Cell membrane ; Peripheral membrane protein . Cytoplasm, cytosol . Mainly localizes in the nucleus, and at low level in the cytosol (PubMed:31808743, PubMed:31544964). On chromosomes, enriched on centromeric satellite and LINE DNA repeat elements (PubMed:30811988). Exported from the nucleus to the cytosol in a XPO1/CRM1 via the nuclear export signal in response to DNA stimulation (PubMed:33406424). Outside the nucleus, localizes at the cell membrane as a peripheral membrane protein in resting conditions: association to the cell membrane is mediated via binding to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) (PubMed:30827685). Localization at the cell membrane is required to limit the recognition of self-DNA (PubMed:30827685). Following detection of double-st
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