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MCLN2 rabbit pAb
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ES15002
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: MCLN2 rabbit pAb
反应性: Human; Mouse
别名: Mucolipin-2
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human MCLN2 AA range: 328-378
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 60kD
基因ID: 255231
蛋白序列: Q8IZK6
细胞定位: Cell membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Localizes to recycling endosomes in activated macrophages and microglia. .
研究背景: Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009],
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