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MDSP rabbit pAb
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ES14986
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: MDSP rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human MDSP AA range: 48-98
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 21kD
基因ID: 51207
蛋白序列: Q6B8I1
细胞定位: Cytoplasm .
研究背景: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008],
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