Synthesized peptide derived from human NAT8L AA range: 218-268
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
33kD
基因ID:
339983
蛋白序列:
Q8N9F0
细胞定位:
Cytoplasm . Microsome membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. .
研究背景:
This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010],