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NBPFC rabbit pAb
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ES14555
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: NBPFC rabbit pAb
反应性: Human;Rat;Mouse;
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human NBPFC AA range: 119-169
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 30kD
蛋白序列: Q5TAG4
细胞定位: Cytoplasm .
研究背景: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This
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