产品中心

NF-κB2 p100 (phospho-Ser866/870) rabbit pAb
一键复制产品信息
ES14500
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
下载说明 ①

Overview

产品名称: NF-κB2 p100 (phospho-Ser866/870) rabbit pAb
反应性: Human;Mouse
别名: Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
宿主: Rabbit
稀释比: WB 1:1000-2000
免疫原: Synthesized phosho peptide around human NF-κB2 p100 (Ser866 and 870)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 100kD
基因ID: 4791
蛋白序列: Q00653
细胞定位: Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
研究背景: nuclear factor kappa B subunit 2(NFKB2) Homo sapiens This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
关闭

在线咨询

Online consultation

  • 在线咨询
  • 技术支持

关注微信公众号

微信扫一扫立即咨询

微信电脑端咨询

微信扫一扫立即咨询

微信电脑端咨询
关闭