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NMRL1 rabbit pAb
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ES14475
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: NMRL1 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human NMRL1 AA range: 179-229
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 33kD
基因ID: 57407
蛋白序列: Q9HBL8
细胞定位: Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Under normal redox growth conditions localizes in the cytoplasm and perinuclear region. Nuclear localization is promoted by increased intracellular nitric oxide and reduced NADPH/NADP(+) ratios.
研究背景: This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015],
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