Synthesized peptide derived from human NOSTN AA range: 309-359
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
56kD
基因ID:
115677
蛋白序列:
Q8IVI9
细胞定位:
[Isoform 1]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Enriched in selected actin structures (PubMed:16234328, PubMed:16376344).; [Isoform 3]: Nucleus .
研究背景:
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004],