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NUDT5 rabbit pAb
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ES14432
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: NUDT5 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human NUDT5 AA range: 95-145
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 24kD
基因ID: 11164
蛋白序列: Q9UKK9
细胞定位: Nucleus .
研究背景: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013],
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