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NUF2 rabbit pAb
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ES14428
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: NUF2 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human NUF2 AA range: 199-249
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 51kD
基因ID: 83540
蛋白序列: Q9BZD4
细胞定位: Nucleus. Chromosome, centromere, kinetochore. Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. NDC80 is required for efficient kinetochore localization.
研究背景: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008],
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