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PCDA8 rabbit pAb
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ES14233
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PCDA8 rabbit pAb
反应性: Human;Rat;Mouse;
别名: Protocadherin alpha-8 (PCDH-alpha-8)
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human PCDA8 AA range: 123-173
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 105kD
基因ID: 56140
蛋白序列: Q9Y5H6
细胞定位: Cell membrane ; Single-pass type I membrane protein .
研究背景: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008],
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